What is HoFH?
Homozygous (Ho) means you inherited the condition from both sides of your family.
Familial (F) means the condition runs in your family.
Hypercholesterolemia (H) means high cholesterol.
Genetic high cholesterol—what does it really mean?
High cholesterol that runs in families is also called familial hypercholesterolemia, or FH. HoFH is the least common and most severe form of FH.
While high cholesterol is common, high cholesterol caused by HoFH is not. In fact, family members on both sides of your family may have a less severe form of FH, but you may be the only one with HoFH.
Why are family and personal health history important?
In HoFH, both parents pass on the
Also, keeping careful records of your own personal health history can help your doctor determine if you have HoFH.
Has it been difficult to reach your cholesterol goals?
You're not alone. People with HoFH who are taking other cholesterol-lowering therapies and following their doctor's advice on eating and exercise often still have trouble lowering their cholesterol to a healthy level.
When other cholesterol-lowering medicines alone may not be enough for people with HoFH
Medications such as statins treat high cholesterol, including more common types of genetic high cholesterol, but are not specifically developed to treat high cholesterol caused by HoFH.
These medications typically rely on the liver's mechanism for removing unused bad (LDL) cholesterol from the bloodstream in order to work. Since this part of your liver doesn't work properly, these medications may not be enough when used alone to help you reach the cholesterol goals set with your doctor.
Adding a medication such as Juxtapid® that is specifically developed to treat high cholesterol caused by HoFH may help further reduce your cholesterol numbers to get closer to the goal set with your doctor.
Why is it important to set a cholesterol goal?
Everyone should strive to keep his or her cholesterol numbers at healthy levels. But as a person living with HoFH, it’s critical for you to keep track of your cholesterol numbers and the goals your doctor has set with you.
Not everyone’s cholesterol goals are the same. Talk to your doctor about setting a cholesterol goal that’s right for you.