Support & Resources

Compass is Ready to Help

To help you add Juxtapid to your current treatment for HoFH and maintain a low-fat eating plan, a Compass support team is built around you, providing the support services and resources you need—when you need them.

What to Expect from Compass when Starting Juxtapid

Personalized Education, Support, and Guidance

Online or In-Person Education Sessions

The Compass Clinical Patient Educator personally guides you through what you need to know about HoFH and cholesterol, how the condition is inherited from both sides of the family, and how it affects your liver, continuing discussions you have had with your doctor. You’ll learn what you can do to help manage HoFH, how Juxtapid works, and steps to get started.

Insurance and Financial Assistance Options

The Compass Nurse Case Manager works to make the insurance process easier for you, helps you understand the cost of your treatment, and can help refer you to independent financial assistance programs. You’ll also find out if you may qualify for the Compass Copay Program, which covers costs of copayments or co-insurance at 100%, up to the program maximum, for eligible patients.

The Compass Copay Program is not valid for prescriptions eligible to be reimbursed, in whole or in part, by state or federally funded healthcare programs such as Medicaid, Medicare, Tricare, VA/DOD, or any state prescription drug assistance programs. Other eligibility requirements may apply. Amryt Pharma reserves the right to discontinue or modify the Compass Copay Program at any time.


Help Customizing Your Low-Fat Eating Plan

A specially trained Compass Clinical Patient Educator consults with you to personalize a low-fat eating plan that works for you. You’ll learn how to create a low-fat eating plan with your food preferences, as well as how this plan differs from a heart-healthy eating plan. You’ll also learn how to use all the information and tools that Compass provides to help you stay on track.

The Compass Clinical Patient Educator will walk you through an informative Nutrition Guide to help incorporate the low-fat eating plan into your daily routine. From meal plans with great recipes to a handy Tracking Notebook to helpful tips and tools, Compass provides the resources you need.


Specialty Pharmacy Services

The Compass Pharmacy Partners at Accredo Specialty Pharmacy answer your questions about Juxtapid. They will help ensure that you receive your medication and recommended nutritional supplements whether you’re at home, at work, or even if you’re traveling or moving.


Learn From Others Like You

Hear about the personal experiences of others with HoFH. You can come to an online or in-person Patient Education Program held over a complimentary lunch or dinner at a restaurant near you. You’ll get more information about the low-fat eating plan, learn about HoFH and Juxtapid, and meet a Compass Clinical Patient Educator.

Helpful Resources

In addition to support programs, Compass also gives you the educational materials you will need to get started with your HoFH treatment and help you stay on track. View and print the resources below by clicking on the DOWNLOAD PDF button.

My Compass Tracker

Everything you will need to record your progress throughout your treatment.



Meal ideas that will help you stay on track with your low-fat eating plan.



Helpful suggestions on how to make better choices when eating out.



A helpful worksheet to track your cholesterol progress.




Indication and Important Safety Information

Juxtapid® (lomitapide) capsules is a prescription medicine used along with diet and other lipid lowering treatments, including low-density lipoprotein (LDL) apheresis where available, in adults with homozygous familial hypercholesterolemia (HoFH) to reduce LDL (“bad”) cholesterol, total cholesterol, a protein that carries bad cholesterol in the blood (apolipoprotein B), and non-high-density lipoprotein cholesterol (non-HDL-C).

Studies have not been conducted to tell us whether Juxtapid can help prevent problems from high cholesterol, such as heart attack, stroke, death, or other health problems. Studies have also not been conducted to tell us whether Juxtapid is safe for use in people with high cholesterol but who do not have HoFH, including those with heterozygous familial hypercholesterolemia (HeFH).

Juxtapid is available only through certified pharmacies that are enrolled in the Juxtapid REMS Program. Your doctor must be enrolled and certified in the program in order to prescribe Juxtapid.

Juxtapid may cause serious side effects, including:

Liver Problems

  • Juxtapid can cause liver problems such as increased liver enzymes or increased fat in the liver. For this reason, your doctor should do blood tests to check your liver before you start Juxtapid and while you are taking Juxtapid (especially if your dose is increased). If your tests show signs of liver problems, your doctor may lower your dose of Juxtapid or stop it altogether.
  • You should tell your doctor if you have had liver problems in the past, including liver problems while taking other medicines.
  • Stomach problems can also be a symptom of liver problems. Tell your doctor right away if you have nausea; vomiting or stomach pain that gets worse, does not go away, or changes; fever; yellowing of your eyes or skin; feeling more tired than usual; or having flu-like symptoms while taking Juxtapid because these may be signs of liver problems.
  • Do not drink more than 1 alcoholic drink per day while taking Juxtapid.

Harm to your unborn baby:

  • Do not take Juxtapid if you are pregnant, think you may be pregnant, or are planning to become pregnant.
  • You should have a negative pregnancy test result before you can start on Juxtapid. Use effective birth control while taking Juxtapid. If you become pregnant while taking Juxtapid, stop taking Juxtapid and call your doctor right away.

You should not take Juxtapid if you:

  • Are taking medications known as moderate or strong CYP3A4 inhibitors (for example, certain medications used to treat bacterial, fungal, or viral infections, as well as certain medications used to treat depression, high blood pressure, or angina). These medications may affect how your body breaks down Juxtapid.
  • Have moderate to severe liver problems or active liver disease, including abnormal liver function tests.

Other possible side effects of Juxtapid:

  • The most common side effects of Juxtapid are stomach problems including diarrhea, nausea, vomiting, cramps/pain, indigestion, and/or gas. You may be able to reduce your chance of stomach problems by following an eating plan consisting of less than 20% of calories from fat.
  • Juxtapid makes it harder for some fat-soluble nutrients, such as vitamin E and fatty acids, to get into your body. Take supplements that contain fat-soluble vitamins each day while you take Juxtapid. Ask your doctor, nurse, or dietitian how to take them.

Tell your doctor if you have any side effect that bothers you or that does not go away. Stop taking Juxtapid and tell your doctor if you have severe diarrhea, especially if you also have lightheadedness, decreased urine output, or tiredness. These are not all the possible side effects of Juxtapid. For more information, speak with your doctor or pharmacist.

Tell your doctor about all the medicines you take, including prescription and non-prescription medicines, vitamins, and herbal supplements. Juxtapid may affect the way other medicines work, and other medicines may affect how Juxtapid works.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit or call 1-800-FDA-1088.

This is the most important information about Juxtapid. For more detailed information, Please see the Medication Guide and full Prescribing Information including Box Warning.